Because you like Karen McCluskey in Desperate Housewives

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Nate Archibald
143

Nate Archibald is confident, shrewd and trying to do the right thing. But that isn't always easy on the ruthless Upper East Side. See them in Gossip Girl.

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Tami Taylor
142

Much more than just "Coach Taylor's wife," Tami Taylor is making herself known in town as a caring, persistent guidance counselor. See them in Friday Night Lights (TV).

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Sydney Bristow
149

Sydney Bristow is a kick-ass double agent on a mission for revenge. See them in Alias.

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Mark Sloan
152

Mark Sloan is the best plastic surgeon and biggest playboy the hospital's ever seen. See them in Grey's Anatomy.

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Winifred Burkle
151

It's impossible to say whether Winifred Burkle is cuter than she is smart, or vice versa. See them in Angel.

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Sabriel
152

Sabriel is smart enough to understand the dangers that await her and brave enough to face them anyway. See them in Abhorsen Series.

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Queen Ravenna
157

Merciless and manipulative, Queen Ravenna is determined to become the fairest of them all. See them in Snow White and the Huntsman.

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Martha Jones
317

A compassionate medical student, Martha Jones has found a Doctor she can really look up to. See them in Doctor Who.

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Peter Venkman
158

Peter Venkman's "research" projects are designed to get undergraduate students to sleep with him. Though it turns out he can bust ghosts. See them in Ghostbusters.

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Cece Parekh
159

Loyal and supportive, Cece Parekh is the best friend a girl could ask for. It doesn't hurt that she's a supermodel. See them in New Girl.

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Phoebe Halliwell
159

Phoebe Halliwell is a bestselling author and martial arts master with power of premonitions. See them in Charmed.

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Derek Shepherd
163

Derek Shepherd is a talented and passionate neurosurgeon. Some people call him McDreamy. See them in Grey's Anatomy.