Because you like Wilbur in Charlotte's Web

Santana Lopez is a cutthroat cheerleader who's not afraid to speak, or sing, her mind. See them in Glee.

Blaine Anderson is a put-together prep school boy with the voice of an angel. See them in Glee.

If anyone can stay optimistic and friendly under harsh alien rule, it's Alyx Vance. See them in Half-Life 2.

Sally Albright is high maintenance who she thinks she's low maintenance. But she's still worth it. See them in When Harry Met Sally....

It's impossible to say whether Winifred Burkle is cuter than she is smart, or vice versa. See them in Angel.

Mark Sloan is the best plastic surgeon and biggest playboy the hospital's ever seen. See them in Grey's Anatomy.

Although she's the queen of killer comebacks and one-liners, Janis Ian is honest about her feelings and cares deeply about her friends. See them in Mean Girls.

Matt Flamhaff is not too concerned about being part of the popular crowd. Too bad his best friend is. See them in 13 Going on 30 .

Most of the world has been wiped out from The Beast. And when The Beast comes, Cole MacGrath will be ready. See them in inFAMOUS.

Lazy and cynical‚ Bernard Black is the ultimate curmudgeon. See them in Black Books.

Fiery and adventurous, Amy Pond is the sort of woman you'd want by your side on a journey through time and space. See them in Doctor Who.

David Rossi may chase serial killers for a living, but he's more interested in what wine pairs well with tonight's parmigiana. See them in Criminal Minds.