Because you like Nozomu Itoshiki in Sayonara, Zetsubo Sensei
Simon Belmont is a vampire hunter bravely carrying on the family business. See them in Castlevania.
Jacob Kowalski is just a baker caught up in an otherworldly adventure. See them in Fantastic Beasts and Where To Find Them.
Thanos is an intergalactic warlord, on the hunt for infinite power. See them in Marvel Cinematic Universe.
White Witch's heart is as frozen as the land she rules. See them in The Chronicles of Narnia.
Daria Morgendorffer is so defensive that she actively works to make people dislike her so that she don't feel bad when they do. See them in Daria.
Megamind is searching for purpose in a supervillain life without a superhero to fight. See them in Megamind.
Jack Skellington is a nightmare-man with a soft heart and smooth voice. See them in The Nightmare Before Christmas.
Louise Belcher might be just a kid, but she can manipulate just about anyone with a pulse. All in the name of fun, of course. See them in Bob's Burgers.
Although life in a post-apocalyptic world is far from easy, Julie Grigio maintains her sense of humor. See them in Warm Bodies.
Brian Griffin is the most scholarly member of the family—when he's not drunk on martinis. See them in Family Guy.