Because you like Sally Albright in When Harry Met Sally...

Yuri Plisetsky's a hotheaded punk off the ice, incredible artist on it. See them in Yuri on Ice.

An alien, a time-traveler, and an esper are following Haruhi Suzumiya, who – unknown to herself – is a near-omnipotent reality warper. See them in The Melancholy of Haruhi Suzumiya.

An ironic hipster with a healthy dose of self-deprecation, Dave strives to be cool at all costs. See them in Homestuck.

Ex-adviser to the king and most powerful sorceress, Yennefer is determined to be even stronger to attain her freedom in a war-torn world. See them in The Witcher.

Misaki Nakahara is keeping tabs on her newest project: recluse Tatsuhiro Sato. See them in Welcome to the NHK.

Stoic, cynical, and independent, Homura Akemi is an alluring enigma. See them in Puella Magi Madoka Magica.

Gou Matsuoka offers to help as manager of a swim team, believing that they're the only ones who can help her brother. See them in Free! Iwatobi Swim Club.

Eren Jaeger will erase the Titans from this world until not a single one remains. See them in Attack on Titan.

Reclusive, quiet, and seemingly emotionless, Lain Iwakura feels like an outsider in her hyper-connected world. See them in Serial Experiments Lain.

Nozomu's name translates to despair, which is fitting for him. See them in Sayonara, Zetsubo Sensei.

A crabby troll, Karkat Vantas is perpetually angry about his lot in life. See them in Homestuck.

Convinced that the world is conspiring against him, Tatsuhiro's reconciled himself to his fate as a shut-in. See them in Welcome to the NHK.