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With great power comes great responsibility, but Peter Parker always seems to get the short end of that bargain. See them in Marvel Cinematic Universe.

A level-headed show business icon despite his amphibian status, Kermit is the brains behind the success of the Muppets. See them in The Muppet Movie.

Veronica Sawyer thinks that if you were happy every day of your life you wouldn't be a human being, you'd be a game-show host. See them in Heathers.

Ramona Flowers is a delivery girl who's been through her fair share of bad breakups. Super-bad breakups! See them in Scott Pilgrim vs. the World.

Foul mouthed and disturbingly comfortable with violence, Hit-Girl is a precocious assassin who doesn't need anyone's protection. See them in Kick-Ass.

If Lisbeth Salander can hurt a bastard who deserves it by digging up stuff about him, she feels good. See them in The Girl with the Dragon Tattoo.

A believer in the pursuit of justice, Garrus Vakarian hates it when bad guys slip through the cracks of the bureaucratic justice system. See them in Mass Effect.

A photographic memory is just one of many skills Lexie Grey brings to the table as a surgeon. See them in Grey's Anatomy.

When their organization was infiltrated by evil HYDRA, who was the one guy Captain America trusted? A former soldier with kickass wings named Sam Wilson. See them in Marvel Cinematic Universe.

Poison Ivy is a seductive, venomous botanist laments the fact that there are so many people to kill, yet so little time. See them in DC Extended Universe.

Wolverine is a hot-blooded Canadian with an adamantium skeleton who's the best at what he does. See them in X-Men Series.