Because you like Duke Nukem in Duke Nukem
Turanga Leela is the daughter of two mutants who live in the sewers below New York City. See them in Futurama.
As the hero of time, Link is reborn throughout history, always with the purpose of fighting and defeating the evil Ganon. See them in The Legend of Zelda.
Philip J. Fry accidentally cryogenically froze himself for a millennium. See them in Futurama.
Kazuma Kiryu's legendary strength and exploits have earned him the nickname of Dragon of Dojima. See them in Yakuza.
Relentlessly cheery Ned Flanders enjoys a nice piece of bread with water on the side for dipping See them in The Simpsons.
A karate master/rocket scientist/squirrel, Sandy Cheeks is the only one who can clean up the other resident's messes in Bikini Bottom. See them in SpongeBob SquarePants.
After being resurrected and discovering his new morphing abilities, Alex Mercer uses them to combat the virus now ravaging New York. See them in Prototype Series.
Hoban Washburne shows you can be a hotshot space pilot *and* play with dinosaurs. See them in Firefly.
Charismatic, sociopathic, and dramatic, Charlie Bronson wants nothing more than to be famous. See them in Bronson.
Kagami Hiiragi keeps her grades up, helps at Takanomiya Shrine, serves as class president, and hangs out with her friends. See them in Lucky Star.
Moe Szyslak is the crabby owner of the grimiest bar in Springfield. See them in The Simpsons.
Roger is a pansexual alcoholic non-human who will happily lie, cheat and steal to get what he wants. See them in American Dad!.