Because you like Domino in Deadpool
Suzy Bishop is only 12, but her withering stare and withdrawn personality are enough to make anyone wilt. See them in Moonrise Kingdom.
With each reboot, Janet progresses more and becomes capable of human emotions. See them in The Good Place.
Sally Albright is high maintenance who she thinks she's low maintenance. But she's still worth it. See them in When Harry Met Sally....
Ava may just be the perfect woman. So long as she can pass a Turing test. See them in Ex Machina.
Gruff and sarcastic, Detective Harry Dresden use unconventional ways to track down perps, including using magic and the supernatural. See them in The Dresden Files.
Courteous, dangerous, and powerful, Kaname Kuran controls an entire court of vampires. Very, very pretty vampires. See them in Vampire Knight.
Nozomu's name translates to despair, which is fitting for him. See them in Sayonara, Zetsubo Sensei.
Brilliant but self-destructive, Lip Gallagher spends more time stirring up trouble than hitting the books. See them in Shameless.
Veronica Mars is a sarcastic private eye whose biggest mission is surviving high school. See them in Veronica Mars.
Susanna Kaysen is an aspiring writer, despairing young woman who struggles with suicidal thoughts. See them in Girl, Interrupted.
A believer in the pursuit of justice, Garrus Vakarian hates it when bad guys slip through the cracks of the bureaucratic justice system. See them in Mass Effect.