Because you like Fish Mooney in Gotham
Empathetic Nausicaa embraces all forms of life, even those that might scare other people. See them in Nausicaa of the Valley of the Wind.
It's a race against time to develop his theory of the origins of the Universe before Stephen Hawking's body and mind give out. See them in The Theory of Everything.
Don't ask the ruthless queen of the Tokyo underworld any questions unless you're fine with losing a limb. See them in Kill Bill vol. 1.
Greg Heffley will be famous someday, but now he's stuck in class with morons. See them in Diary of a Wimpy Kid.
Matilda Wormwood is so smart, she taught herself how to be psychic. See them in Matilda.
Tifa Lockhart is part mother hen, part martial arts bad-ass. See them in Final Fantasy Series.
Ichigo Momomiya is a bubbly student by day, magical cat-powered superhero by night. See them in Tokyo Mew Mew.
A self-professed psychopath, James kills small animals for fun. After getting bored of that, he is ready for an ambitious murder. See them in The End of the F World.
Cher Horowitz may have a problem with hubris, but she looks utterly fabulous while learning a lesson about the dangers of meddling. See them in Clueless.
Both intelligent and empathetic, Remus Lupin is worn down by the weight of a secret. See them in Harry Potter Series.