Because you like Alex Karev in Grey's Anatomy
Elaine Benes is a tough New Yorker who can hang with the guys, and date the ones who are "sponge-worthy." See them in Seinfeld.
When their organization was infiltrated by evil HYDRA, who was the one guy Captain America trusted? A former soldier with kickass wings named Sam Wilson. See them in Marvel Cinematic Universe.
Megamind is searching for purpose in a supervillain life without a superhero to fight. See them in Megamind.
Give in to the dark side with vampire Lestat; it's more fun. See them in Interview with the Vampire: The Vampire Chronicles.
Cher Horowitz may have a problem with hubris, but she looks utterly fabulous while learning a lesson about the dangers of meddling. See them in Clueless.
Leonard "Bones" McCoy is passionate, moral, and ready to stitch you back together. See them in Star Trek.
Her unhappy childhood has left her unsure of the existence of happy endings. Mary Jane Watson hides her pain beneath a joke and a smile. See them in Marvel Cinematic Universe.
Casey Gardner is an angsty teenage girl with quite a bit of sass that keeps getting her in trouble. See them in Atypical.
Wendy Corduroy is the ultimate in cool in Gravity Falls. See them in Gravity Falls.
For someone who swears she doesn't care for anyone, MJ Jones spends a lot of time observing her classmate Peter Parker. See them in Marvel Cinematic Universe.
Taking down villains, standing up to sexism, and pulling off a bright-red lipstick are all in a day's work for Agent Peggy Carter. See them in Marvel Cinematic Universe.