Because you like Sue Sylvester in Glee
An obsessive schoolgirl, Yuno has two sides to her personality, and both are equally unnerving. See them in The Future Diary.
She got locked up so her husband could make it big, but now Cookie Lyon is coming for what's hers. See them in Empire.
If it means fulfilling her ambitions, Satsuki Kiryuin will show neither shame nor hesitation. See them in Kill la Kill.
Ron Burgundy is a news anchor who signs off with "Stay classy, San Diego" or whatever his teleprompter says. Bonus: he plays the jazz flute. See them in Anchorman: The Legend of Ron Burgundy.
Convinced that the world is conspiring against him, Tatsuhiro's reconciled himself to his fate as a shut-in. See them in Welcome to the NHK.
Wanderer is a Soul, a parasite sent into a host to take over their body, extracting information from them and colonizing their species. See them in The Host.
Raz is a 10-year-old boy who mostly stays in his own head, which makes sense since that's where he is strongest. See them in Psychonauts.
Misaki Nakahara is keeping tabs on her newest project: recluse Tatsuhiro Sato. See them in Welcome to the NHK.
Spike Spiegel is a bounty-hunter with a laidback style and lightning-quick moves. See them in Cowboy Bebop.
Not only could Hellboy avenge your death, he'd also have a sense of humor about it and not let it ruin the rest of his night. See them in Hellboy.