Because you like Susan Mayer in Desperate Housewives
Miles Morales was bitten by a radioactive spider, put on the webbed spandex, and beat up his first bad guy before his voice changed. See them in Marvel Cinematic Universe.
Although Morrigan knows every kind of magic there is, friendship is an untested area for her. See them in Dragon Age Series.
It's hard enough fighting a war. But it's worse for Commander Shepard, knowing no matter how hard you try, you can't save them all. See them in Mass Effect.
Rose Hathaway is a reckless, rebellious smartass who's training to be a royal vampire guardian. See them in Vampire Academy.
An aristocrat-turned-tomb-raider, Lara Croft does her best thinking while plunging off cliffs. See them in Lara Croft: Tomb Raider.
Stoic, cynical, and brilliant, Solid Snake was genetically engineered to be the perfect soldier. See them in Metal Gear Series.
Whether he's performing "illusions" or running the family business, one thing is certain: Gob Bluth will screw it up. See them in Arrested Development.
With her consciousness so easily shifted between bodies, Motoko Kusanagi is left unsure of who or what she really is. See them in Ghost in the Shell.
Motivated by a strong sense of curiosity, fleet-footed Lina Mayfleet is happiest when she's on the move. See them in The City of Ember.
Ava may just be the perfect woman. So long as she can pass a Turing test. See them in Ex Machina.
Regina Mills is a cold evil queen turned chilly town mayor. See them in Once Upon a Time.
When it comes to flattery, manipulation, and politics, Oswald Cobblepot can play with the best of them. See them in Gotham.