Because you like Naota Nandaba in FLCL
Nozomu's name translates to despair, which is fitting for him. See them in Sayonara, Zetsubo Sensei.
Firo Prochainezo is swept up in a world of mysterious women, alchemists, and rumors of a wine that makes it drinkers immortal. See them in Baccano!.
Shana is a red-haired warrior with a black-and-white worldview. See them in Shakugan no Shana.
Gou Matsuoka offers to help as manager of a swim team, believing that they're the only ones who can help her brother. See them in Free! Iwatobi Swim Club.
The vampire that killed Zero Kiryu's family also infected him, and he starts to crave blood, much to his horror. See them in Vampire Knight.
The "runt" of his biker gang, Tetsuo Shima grapples with a perpetual inferiority complex. See them in Akira.
If there's power in being average, Mikado Ryugamine will find it and use it. See them in Durarara!!.
Given his ability to wrench street signs from the ground, Shizuo Heiwajima is a useful one to have in dangerous Ikekuburo. See them in Durarara!!.
Everyone is just a chess piece, and Izaya Orihara is a master player. See them in Durarara!!.
The Sohma family is just plain cursed, and Yuki Sohma has to learn to live with it – or so he thinks. See them in Fruits Basket.
For somebody who won't answer questions, the enigmatic C.C. sure asks a lot of them. See them in Code Geass.