Because you like Jason "J.D." Dean in Heathers
Her interests include martial arts, interrogation, and hacking. Natasha Romanoff is the ultimate spy. See them in Marvel Cinematic Universe.
Walter White's knowledge of chemistry allows him to cook astoundingly pure meth, leading to a rapid – albeit tumultuous – rise in the criminal drug world. See them in Breaking Bad.
Duck, girl, and legend: Ahiru's identities confuse even herself at times, and she often wonders which of them is truly her. See them in Princess Tutu.
Meat Boy tenaciously throws himself into danger, and when he fails, he immediately gets back up and tries again. See them in Super Meat Boy.
Don't worry about this forensic scientist offing you unless you're a serial killer yourself. (You're not, right? Just checking.) See them in Dexter.
Bedside manner is for chumps, not the brilliant Dr. Gregory House. See them in House M.D..
Good fashion? Check. Snarky quips? Check. Supernatural evil-fighting powers? Also check. See them in Buffy the Vampire Slayer.
This suave con-man doesn't just want to become rich. Danny Ocean wants to rip off the guy who stole his wife in the biggest Vegas con. See them in Ocean's Eleven.
Red doesn't like to explain herself. She wants her work to do the talking. See them in Transistor.
A vampire hunter, Integra Hellsing doesn't tolerate failure, least of all her own. See them in Hellsing.