Because you like Malcolm Sayer in Awakenings
A superpowered test subject, Scarlet Witch can manipulate other people's thoughts and force them to confront their worst fears. See them in Marvel Cinematic Universe.
A wildly brilliant detective, Sherlock Holmes can figure out everything except how to interact with other human beings. See them in Sherlock.
John Watson is haunted by his past (who isn't) but he's starting to branch out with some help from a world class detective. See them in Sherlock.
Albus Dumbledore oversees the most unsafe school in recorded history, with Dementors and giant arachnids run amok. See them in Harry Potter Series.
WALL-E is a quirky little romantic robot cleaning the wasteland known as Earth. See them in WALL-E.
Both intelligent and empathetic, Remus Lupin is worn down by the weight of a secret. See them in Harry Potter Series.
Sheldon Cooper is brilliant in every way except, well, interacting with any human being. See them in The Big Bang Theory.
Daenerys Targaryen will take what is hers with fire and blood. Thankfully, she has some dragons by her side. See them in Game of Thrones.
His elfin self-confidence can border on pretension, but Legolas Greenleaf is a fearsome fighter and a loyal friend. See them in The Lord of the Rings.
As a scaring Assistant, Mike Wazowski frightens children to collect their screams to be used as a power supply for the city. See them in Monsters, Inc..
With his own ship, Peter Quill calls his own shots, and gets to fly from planet to planet blasting '70s pop hits and picking up alien chicks. See them in Marvel Cinematic Universe.
Brilliant, violent, and only a little insane, the Joker doesn't listen to anyone except the voices in his head. See them in DC Extended Universe.