Because you like Hal 9000 in 2001: A Space Odyssey
Daria Morgendorffer is so defensive that she actively works to make people dislike her so that she don't feel bad when they do. See them in Daria.
Firo Prochainezo is swept up in a world of mysterious women, alchemists, and rumors of a wine that makes it drinkers immortal. See them in Baccano!.
The singer and ukulele player of her girl band, Sugar "Kane" Kowalczyk is the life of a party and the woman of a man's dreams. See them in Some Like It Hot.
Wanderer is a Soul, a parasite sent into a host to take over their body, extracting information from them and colonizing their species. See them in The Host.
They say they saved Adam Jensen by turning him into a cyborg, but he's not sure saved is the right word. See them in Deus Ex Series.
Don't underestimate Maggie Greene. She's a farm girl with a mission. See them in The Walking Dead.
Offred wisely keeps her head down even as she hopes for more. Unfortunately, hope is dangerous in Gilead. See them in The Handmaid's Tale.
Chicken resterauntier by day and drug overlord by night, Gus Fring doesn't let the stress of living a double life get to him. See them in Breaking Bad.
Jade Jade Harley might not be the best at reading social cues, but her bravery and selflessness means she's a great friend to have. See them in Homestuck.
Not only could Hellboy avenge your death, he'd also have a sense of humor about it and not let it ruin the rest of his night. See them in Hellboy.
Kathryn Merteuil may be a vain sociopath, but you won't be able to look away. See them in Cruel Intentions.