Because you like Pam Beesly in The Office
A wildly brilliant detective, Sherlock Holmes can figure out everything except how to interact with other human beings. See them in Sherlock.
Castiel might be an immortal angel, but the human world is still more than a little confusing. See them in Supernatural.
Other people's opinions have never mattered much to Haruka Nanase, and they aren't going to start to do so now. See them in Free! Iwatobi Swim Club.
A rebellious blue-haired art student, Karou has mysterious connections to a magical world. See them in Daughter of Smoke and Bone .
CIA operative Carrie Mathison is on a self-assigned mission to follow a lead, whether it be the truth or just her delusions playing tricks. See them in Homeland.
Rue is an icy prima ballerina whose obsession with perfection obscures a hidden desire to be loved. See them in Princess Tutu.
After alien Haruko rides in on her Vespa, giant robots spouting from Naota Nandaba's forehead soon become the least of his worries. See them in FLCL.
Whether she's working as a mild-mannered assistant or an all-powerful superhero, Kara Danvers is defined above all by her huge heart. See them in Supergirl.
Undercover as an average high school student, Kallen Stadtfeld is actually most at ease when the action's fast, furious, and dangerous. See them in Code Geass.
Emmet Brickowski is so upbeat it's not even human. Everything is AWESOME! See them in The Lego Movie.
A fight every now and then makes Dante's life a little more interesting. See them in Devil May Cry.
Pro tip: the psych ward is not the best place to find a mentor like Lisa Rowe. See them in Girl, Interrupted.