Because you like Darcy Lewis in Thor
Maka is determined to collect and purify 99 Kishin eggs– human souls that have been corrupted by evil– and one witch soul. See them in Soul Eater.
An alien, a time-traveler, and an esper are following Haruhi Suzumiya, who – unknown to herself – is a near-omnipotent reality warper. See them in The Melancholy of Haruhi Suzumiya.
It's hard to tell if Dean Winchester cares more about saving the world or his 1967 Chevy Impala. See them in Supernatural.
Walter White's knowledge of chemistry allows him to cook astoundingly pure meth, leading to a rapid – albeit tumultuous – rise in the criminal drug world. See them in Breaking Bad.
The son of Death has an obsession with perfection and symmetry. See them in Soul Eater.
Duck, girl, and legend: Ahiru's identities confuse even herself at times, and she often wonders which of them is truly her. See them in Princess Tutu.
A fourth grader without a moral compass, Eric Cartman lives on KFC, Taco Bell, Pizza Hut, and Cheesy Poofs. See them in South Park.
A powerful dragon-hunting warrior, Dovahkiin is destined for great things. See them in The Elder Scrolls V: Skyrim.
Raiden is an efficient soldier haunted by his repressed past. See them in Metal Gear Series.
Stewie Griffin is just your average evil-genius, talking, sociopathic baby. See them in Family Guy.
John Locke is an eerily calm, confident believer in the magic of the island that gave him his legs back. See them in Lost.
A crabby troll, Karkat Vantas is perpetually angry about his lot in life. See them in Homestuck.