Because you like Mark Watney in The Martian
Anna Karenina doesn't want to be a respectable woman any more. She thinks respect was invented to cover the empty place where love should be. See them in Anna Karenina.
Fiery, intelligent, and opinionated, Jo March rebels against the restrictions of her era. See them in Little Women.
Don't worry about this forensic scientist offing you unless you're a serial killer yourself. (You're not, right? Just checking.) See them in Dexter.
Clementine is a beacon of innocence in a dangerous, deadly world. See them in The Walking Dead (Video Game).
Though Ray Holt is a man of few words and even fewer smiles, he cares deeply about his precinct and detectives. See them in Brooklyn Nine-Nine.
Though she can seamlessly flit between glamorous identities, Sydney Prosser is more vulnerable than she pretends to be. See them in American Hustle.
Bedside manner is for chumps, not the brilliant Dr. Gregory House. See them in House M.D..
Sheldon Cooper is brilliant in every way except, well, interacting with any human being. See them in The Big Bang Theory.
Jenna Rink is physically 30 but emotionally 13. She has a better excuse than most. See them in 13 Going on 30.
His murderous megalomania aside, Loki is quite charming. Just don't mention his strapping older brother; he's a tad jealous. See them in Marvel Cinematic Universe.
Big Boss is a disillusioned mercenary commander who wants to create a world for soldiers (and soldiers alone). See them in Metal Gear Series.
Billy Batson is a troublemaking teen grappling with a pretty weird superhero identity crisis See them in DC Extended Universe.