Because you like Annie Wilkes in Misery

It's time somebody has to take over. It might as well be Fish Mooney. See them in Gotham.

Howl puts the "tortured" in tortured artist. He just wants to be recognized for his work, but no one wants to trust a boy that sorta looks like a bird. See them in Howl's Moving Castle.

Just a hint of human emotion lurks under the enigmatic exterior of Rei Ayanami. See them in Neon Genesis Evangelion.

If Yuri Katsuki can boost his confidence, he will win over the crowds with his artistry. See them in Yuri on Ice.

A vampire hunter, Integra Hellsing doesn't tolerate failure, least of all her own. See them in Hellsing.

A malevolent dark wizard, Voldemort is so fearsome that he's known primarily as "He Who Must Not Be Named." See them in Harry Potter Series.

With an A.I. as loyal and witty as Cortana, who needs humans? See them in Halo.

Although Mako Mori may be small and quiet, she is a core of battle-hardened steel. See them in Pacific Rim.

Vengeance is William Wallace’s game. With his father, brother, and wife killed by the English, he slaughters the garrison and sacks cities. See them in Braveheart.

Sylar's victims are found all over the country, many with their brains removed. See them in Heroes.

A fight every now and then makes Dante's life a little more interesting. See them in Devil May Cry.

R2-D2 has been in the galaxy saving business for decades. Not bad for somebody whose vocabulary is limited to "beep-boop." See them in Star Wars Series.