Because you like Susie Carmichael in Rugrats
Alex Danvers is a brilliant engineer tasked with alien threats, and one of those aliens is her adopted sister Supergirl. See them in Supergirl.
Rupert Giles is a librarian on the outside, fearless evil-fighter on the inside. See them in Buffy the Vampire Slayer.
Gordie Lachance never had any friends later on like the ones he had when I was twelve. See them in Stand By Me.
As a doctor-in-training, John Dorian should have his head in the game. But most of the time, it's in the clouds. See them in Scrubs.
A karate master/rocket scientist/squirrel, Sandy Cheeks is the only one who can clean up the other resident's messes in Bikini Bottom. See them in SpongeBob SquarePants.
Lane Kim is the drummer for Hep Alien, but don't let her mom know. See them in Gilmore Girls.
Anya Jenkins has a real harsh bark to go with her demonic bite. See them in Buffy the Vampire Slayer.
Tina Cohen-Chang is a shy loner who becomes a fierce performer on stage. See them in Glee.
Joey Potter is a low-key girl next door in love with her best friend. See them in Dawson's Creek.
Toby Cavanaugh has trouble avoiding being manipulated. See them in Pretty Little Liars.
Topanga Lawrence has been a put-together intellectual since basically the moment she could talk. See them in Boy Meets World.