Because you like Dorothy Gale in The Wizard of Oz
An alien, a time-traveler, and an esper are following Haruhi Suzumiya, who – unknown to herself – is a near-omnipotent reality warper. See them in The Melancholy of Haruhi Suzumiya.
Beneath Yuji Sakai's meek exterior lies an exceptionally keen mind and a strong inner will. See them in Shakugan no Shana.
Barbara Kean is loving, selfless, and caring. But, she's less stable than she'd like to admit. See them in Gotham.
Duck, girl, and legend: Ahiru's identities confuse even herself at times, and she often wonders which of them is truly her. See them in Princess Tutu.
If anyone can stay optimistic and friendly under harsh alien rule, it's Alyx Vance. See them in Half-Life 2.
Usagi Tsukino may look like a lazy teen, but when Usagi conjures up her alter ego and calls her Sailor Scout team, no villain stands a chance. See them in Sailor Moon.
Moving is hard for Coraline Jones; accidentally moving to a creepy mirror world just makes it harder. See them in Coraline.
A fun-loving gangster's wife, Mia Wallace is finding that fun can go too far. See them in Pulp Fiction.
The "runt" of his biker gang, Tetsuo Shima grapples with a perpetual inferiority complex. See them in Akira.
If there's power in being average, Mikado Ryugamine will find it and use it. See them in Durarara!!.
After alien Haruko rides in on her Vespa, giant robots spouting from Naota Nandaba's forehead soon become the least of his worries. See them in FLCL.