Because you like Clarice Starling in The Silence of the Lambs

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Frank N. Furter
1895

Frank N. Furter is just a sweet transvestite with some not-so-sweet plans. See them in The Rocky Horror Picture Show.

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Poison Ivy
1776

Poison Ivy is a seductive, venomous botanist laments the fact that there are so many people to kill, yet so little time. See them in DC Extended Universe.

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Natasha Romanoff / Black Widow
3514

Her interests include martial arts, interrogation, and hacking. Natasha Romanoff is the ultimate spy. See them in Marvel Cinematic Universe.

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Sarah Manning
655

Cutting ties with her con-artist friends, Sarah Manning is creating a better life for her daughter by taking on the identity of the deceased Beth. See them in Orphan Black.

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Mickey Milkovich
776

Don't mess with Mickey Milkovich unless you want to see the wrong side of one of his many guns. See them in Shameless.

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John Yossarian
179

John Yossarian is trapped in irony as he must be insane to leave the war but if he does try to leave, he'll be deemed sane and will be forced to stay, See them in Catch-22.

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Carl Fredricksen
2872

Carl Fredricksen is a crotchety old man who may just have it in him to take one last, great adventure. See them in Up.

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Charles Xavier / Professor X
2098

Charles Xavier is a telepath who believes mutants and humans are both good at heart and can live in harmony. See them in X-Men Series.

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Jesse Pinkman
1858

Academics weren't his strong suit. Luckily, Jesse Pinkman's street smarts are a cut above the rest. See them in Breaking Bad.

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Hellboy
1319

Not only could Hellboy avenge your death, he'd also have a sense of humor about it and not let it ruin the rest of his night. See them in Hellboy.

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Optimus Prime
1079

Optimus Prime is a shapeshifting sentient robot leading a team of robots to stop evil from taking over. See them in Transformers.

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Jade Harley
240

Jade Jade Harley might not be the best at reading social cues, but her bravery and selflessness means she's a great friend to have. See them in Homestuck.