Pinky and Brain features genetically engineered mouse supergeniuses. Brain (which stands for "Biological Recombinant Algorithmic Intelligence Nexus") lives in ACME Laboratories along with his excitable, dim-witted friend Pinky. Every night Brain conceives and sets into motion a plan to take over the world. World domination is his singular goal in life; failure is not an option. Unfortunately, failure is the perpetual outcome.