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Mitochondria are tiny structures located inside our cells that carry out the essential task of producing energy for the cell. They are found in all complex living things, and in that sense, they are fundamental for driving complex life on the planet. But there is much more to them than that. Mitochondria have their own DNA, with their own small collection of genes, separate from those in the cell nucleus. It is thought that they were once bacteria living independent lives. Their enslavement within the larger cell was a turning point in the evolution of life, enabling the development of complex organisms and, closely related, the origin of two sexes. Unlike the DNA in the nucleus, mitochondrial DNA is passed down exclusively (or almost exclusively) via the female line. That's why it has been used by some researchers to trace human ancestry daughter-to-mother, to 'Mitochondrial Eve'. Mitochondria give us important information about our evolutionary history. And that's not all. Mitochondrial genes mutate much faster than those in the nucleus because of the free radicals produced in their energy-generating role. This high mutation rate lies behind our ageing and certain congenital diseases. The latest research suggests that mitochondria play a key role in degenerative diseases such as cancer, through their involvement in precipitating cell suicide. Mitochondria, then, are pivotal in power, sex, and suicide. In this fascinating and thought-provoking book, Nick Lane brings together the latest research findings in this exciting field to show how our growing understanding of mitochondria is shedding light on how complex life evolved, why sex arose (why don't we just bud?), and why we age and die. This understanding is of fundamental importance, both in understanding how we and all other complex life came to be, but also in order to be able to control our own illnesses, and delay our degeneration and death. Oxford Landmark Science books are 'must-read' classics of modern science writing which have crystallized big ideas, and shaped the way we think.

The author relates his experiences in the State Department during a period that witnessed World War II, European reconstruction, the Korean War and McCarthyism

The creator of the FBI's Art Crime Team recounts his dramatic career, describing high-stakes undercover missions involving valuable stolen antiquities, in an account that covers his role in a famous unsolved crime.

Just when Mia thinks life will be back to normal, her indomitable grandmere schedules a national television interview for Mia, her best friend Lilly styles herself Svangali to an Indiana newcomer, and her mother starts dating her algebra teacher.

New York Times bestselling author Jessica Day George re-imagines the classic fairy-tale, The Twelve Dancing Princesses, in this start to an enchanting YA fantasy series. Rose is one of twelve princesses--sisters condemned to dance every night in the palace of the King Under Stone. Galen is a young soldier returning from war. Together they will search for a way to break the curse that forces the princesses to attend the endless midnight balls. All they need is an invisibility cloak, a black wool chain knit with silver needles, and that most critical fairy tale ingredient--true love. Don't miss these other stories from New York Times bestselling author Jessica Day George: The Twelve Dancing Princesses series Princess of the Midnight Ball Princess of Glass Princess of the Silver Woods Sun and Moon, Ice and Snow Silver in the Blood The Rose Legacy series The Rose Legacy Tuesdays at the Castle series Tuesdays at the Castle Wednesdays in the Tower Thursdays with the Crown Fridays with the Wizards Saturdays at Sea Dragon Slippers series Dragon Slippers Dragon Flight Dragon Spear

Princess Mia's junior year in high school begins with a difficult course load, a crazy student council race, Grandmere's search for temporary lodging, and learning that her boyfriend is moving to Japan for a year, partly because she will not sleep with him.

A spiteful fairy. A beautiful princess. An outstretched finger. A spindle. A hundred-year snooze. A charming prince. A kiss. All the familiar ingredients. But wait! Where did that extra prince come from? And those fairy gifts that were never there before? And what does a flock of balding sheep have to do with anything? Gail Carson Levine has waved her magic wand over the old standby of "Sleeping Beauty" and presto! It reappears, transformed, sparkling and hilarious. Chuckles and giggles are guaranteed.

An ancient prophecy divides two sisters- One good... One evil... Who will prevail? Twin sisters Lia and Alice Milthorpe have just become orphans. They have also become enemies. As they discover their roles in a prophecy that has turned generations of sisters against each other, the girls find themselves entangled in a mystery that involves a tattoo-like mark, their parents' deaths, a boy, a book, and a lifetime of secrets. Lia and Alice don't know whom they can trust. They just know they can't trust each other.

The second book in the New York Times bestselling series from the fantasy author who is a legend herself: TAMORA PIERCE. When they think you will fail . . . fail to listen. As the only female page in history to pass the first year of training to become a knight, Keladry of Mindelan is a force to be reckoned with. But even with her loyal circle of friends at her side, Kel’s battle to prove herself isn’t over yet. She is still trying to master her paralyzing fear of heights and keep up with Lord Wyldon’s grueling training schedule. When a group of pages is trapped by bandits, the boys depend on Kel to lead them to safety. The kingdom’s nobles are beginning to wonder if she can succeed far beyond what they imagined. And those who hate the idea of a female knight are getting desperate—they will do anything to thwart her progress. More timely than ever, the Protector of the Small series is Anti-Bullying 101 while also touching on issues of bravery, friendship, and dealing humanely with refugees against a backdrop of an action-packed fantasy adventure. "Tamora Pierce's books shaped me not only as a young writer but also as a young woman. She is a pillar, an icon, and an inspiration. Cracking open one of her marvelous novels always feels like coming home." —SARAH J. MAAS, #1 New York Times bestselling author "Tamora Pierce didn't just blaze a trail. Her heroines cut a swath through the fantasy world with wit, strength, and savvy. Her stories still lead the vanguard today. Pierce is the real lioness, and we're all just running to keep pace." —LEIGH BARDUGO, #1 New York Times bestselling author

A panoramic and epic novel in the grand romantic style, Push Not the River is the rich story of Poland in the late 1700s--a time of heartache and turmoil as the country's once peaceful people are being torn apart by neighboring countries and divided loyalties. It is then, at the young and vulnerable age of seventeen, when Lady Anna Maria Berezowska loses both of her parents and must leave the only home she has ever known. With Empress Catherine's Russian armies streaming in to take their spoils, Anna is quickly thrust into a world of love and hate, loyalty and deceit, patriotism and treason, life and death. Even kind Aunt Stella, Anna's new guardian who soon comes to personify Poland's courage and spirit, can't protect Anna from the uncertain future of the country. Anna, a child no longer, turns to love and comfort in the form of Jan, a brave patriot and architect of democracy, unaware that her beautiful and enigmatic cousin Zofia has already set her sights on the handsome young fighter. Thus Anna walks unwittingly into Zofia's jealous wrath and darkly sinister intentions. Forced to survive several tragic events, many of them orchestrated by the crafty Zofia, a strengthened Anna begins to learn to place herself in the way of destiny--for love and for country. Heeding the proud spirit of her late father, Anna becomes a major player in the fight against the countries who come to partion her beloved Poland. Push Not the River is based on the true eighteenth century diary of Anna Maria Berezowska, a Polish countess who lived through the rise and fall of the historic Third of May Constitution. Vivid, romantic, and thrillingly paced, it paints the emotional and unforgettable story of the metamorphosis of a nation--and of a proud and resilient young woman.